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Paul W Hake Selected Research

ciglitazone

1/2010Ciglitazone, a novel inhibitor of lung apoptosis following hemorrhagic shock.
10/2008Ciglitazone ameliorates lung inflammation by modulating the inhibitor kappaB protein kinase/nuclear factor-kappaB pathway after hemorrhagic shock.
11/2007Diverse cardioprotective signaling mechanisms of peroxisome proliferator-activated receptor-gamma ligands, 15-deoxy-Delta12,14-prostaglandin J2 and ciglitazone, in reperfusion injury: role of nuclear factor-kappaB, heat shock factor 1, and Akt.
12/2003Peroxisome proliferator activator receptor-gamma ligands, 15-deoxy-Delta(12,14)-prostaglandin J2 and ciglitazone, reduce systemic inflammation in polymicrobial sepsis by modulation of signal transduction pathways.

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Paul W Hake Research Topics

Disease

12Sepsis (Septicemia)
11/2019 - 09/2003
10Inflammation (Inflammations)
04/2011 - 02/2003
9Lung Injury
11/2019 - 09/2003
9Hemorrhagic Shock
01/2018 - 10/2008
9Hemorrhage
10/2017 - 01/2008
7Hypotension (Low Blood Pressure)
01/2018 - 05/2002
7Myocardial Ischemia (Ischemic Heart Diseases)
01/2014 - 02/2002
6Reperfusion Injury
01/2014 - 05/2003
4Ischemia
05/2011 - 02/2002
4Pneumonia (Pneumonitis)
05/2011 - 10/2008
4Myocardial Reperfusion Injury
11/2007 - 02/2002
3Endotoxemia
04/2014 - 05/2007
3Colitis
01/2008 - 05/2003
3Shock
05/2007 - 05/2002
2Edema (Dropsy)
10/2018 - 01/2008
2Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
12/2004 - 05/2003
2Multiple Organ Failure (MODS)
12/2003 - 09/2003
1Acute Lung Injury
11/2019
1Infections
04/2014
1Atherosclerosis
04/2011
1Dermatitis
04/2011
1Ulcer
01/2008
1Diabetic Neuropathies (Diabetic Neuropathy)
05/2007
1Acquired Immunodeficiency Syndrome (AIDS)
05/2007

Drug/Important Bio-Agent (IBA)

11NF-kappa B (NF-kB)IBA
10/2010 - 02/2002
10LigandsIBA
01/2014 - 12/2003
8PPAR gammaIBA
01/2010 - 12/2003
6CytokinesIBA
11/2019 - 12/2003
5Biological ProductsIBA
10/2010 - 09/2003
5Transcription Factor AP-1 (Transcription Factor AP 1)IBA
01/2008 - 12/2003
4Ringer's LactateIBA
01/2018 - 01/2017
4Peroxisome Proliferator-Activated Receptors (PPAR)IBA
04/2014 - 01/2010
4Peroxidase (Myeloperoxidase)IBA
01/2014 - 03/2005
4ciglitazoneIBA
01/2010 - 12/2003
4Poly (ADP-Ribose) Polymerase-1IBA
03/2005 - 05/2003
3AMP-Activated Protein KinasesIBA
11/2019 - 01/2018
3AICA ribonucleotide (ZMP)IBA
10/2018 - 01/2017
3Liver X ReceptorsIBA
08/2015 - 08/2006
3Therapeutic UsesIBA
08/2015 - 05/2007
3C-PeptideIBA
04/2014 - 05/2007
3Transcription Factors (Transcription Factor)IBA
11/2010 - 08/2006
3TeaIBA
01/2008 - 01/2004
3EnzymesIBA
03/2005 - 05/2003
3parthenolideIBA
09/2003 - 02/2002
2Troponin IIBA
10/2018 - 01/2014
2Metformin (Glucophage)FDA LinkGeneric
01/2018 - 10/2017
2Interleukin-6 (Interleukin 6)IBA
05/2011 - 10/2008
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
10/2010 - 05/2007
2ChemokinesIBA
10/2010 - 05/2007
2Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
10/2008 - 05/2007
2epigallocatechin gallate (epigallocatechin-3-gallate)IBA
01/2008 - 09/2007
2PolyphenolsIBA
09/2007 - 01/2004
2Poly(ADP-ribose) Polymerase InhibitorsIBA
03/2005 - 05/2003
2Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
05/2003 - 02/2003
2Creatine Kinase (Creatine Phosphokinase)IBA
03/2002 - 02/2002
14- hydroxy- 3- (4- (2- hydroxyphenyl)phenyl)- 6- oxo- 7H- thieno(2,3- b)pyridine- 5- carbonitrileIBA
11/2019
1FollistatinIBA
10/2018
1MyokinesIBA
10/2018
1Trace Elements (Biometals)IBA
04/2014
1ZincIBA
04/2014
1LeptinIBA
10/2012
1Interleukin-1 (Interleukin 1)IBA
05/2011
1T0901317IBA
04/2011
1Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
11/2010
1Phosphotransferases (Kinase)IBA
11/2010
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
11/2010
1AdipokinesIBA
11/2010
1AdiponectinIBA
11/2010
1PPAR deltaIBA
10/2010
1cyclopentenoneIBA
06/2009
1ProstaglandinsIBA
06/2009
1Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
06/2009
1Protein Kinases (Protein Kinase)IBA
10/2008
1Interleukin-10 (Interleukin 10)IBA
10/2008
1Catechin (Z 7300)IBA
01/2008
1Trinitrobenzenesulfonic AcidIBA
01/2008
1Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
11/2007
12-chloro-5-nitrobenzanilideIBA
11/2007
1Insulin (Novolin)FDA Link
05/2007
1ProinsulinIBA
05/2007
1LipopolysaccharidesIBA
05/2007
115-deoxyprostaglandin J2IBA
07/2005
13-aminobenzamideIBA
03/2005
11,5-dihydroxyisoquinolineIBA
03/2005
1DNA (Deoxyribonucleic Acid)IBA
04/2004
1gallocatechol (epigallocatechin)IBA
01/2004
115-deoxy-delta(12,14)-prostaglandin J2IBA
12/2003
1Sulfonic AcidsIBA
05/2003
1Norepinephrine (Noradrenaline)FDA LinkGeneric
05/2002
1EndotoxinsIBA
05/2002
1Escherichia coli endotoxinIBA
05/2002
1Nitric Oxide (Nitrogen Monoxide)FDA Link
03/2002
1Nitric Oxide Synthase (NO Synthase)IBA
03/2002
1SesquiterpenesIBA
02/2002
1LactonesIBA
02/2002

Therapy/Procedure

10Punctures
11/2019 - 09/2003
10Ligation
11/2019 - 09/2003
8Resuscitation
01/2018 - 06/2009
2Rectal Administration
01/2008 - 05/2003
1Therapeutics
10/2010